Dr. Roberto Augusto Ferriz Martínez

Dr. Ernesto Sabath 



Dr. Juan Manuel Malda Barrera

Evol Bioinform Online. 2014 Jun 29;10:97-105. doi: 10.4137/EBO.S14457. eCollection 2014.

Influence of modularity and regularity on disparity of atelostomata sea urchins.

López-Sauceda J1Malda-Barrera J2Laguarda-Figueras A3Solís-Marín F3Aragón JL4.


A modularity approach is used to study disparity rates and evolvability of sea urchins belonging to the Atelostomata superorder. For this purpose, the pentameric sea urchin architecture is partitioned into modular spatial components and the interference between modules is quantified using areas and a measurement of the regularity of the spatial partitions. This information is used to account for the variability through time (disparity) and potential for morphological variation and evolution (evolvability) in holasteroid echinoids. We obtain that regular partitions of the space produce modules with high modular integrity, whereas irregular partitions produce low modular integrity; the former ones are related with high morphological disparity (facilitation hypothesis). Our analysis also suggests that a pentameric body plan with low regularity rates in Atelostomata reflects a stronger modular integration among modules than within modules, which could favors bilaterality against radial symmetry. Our approach constitutes a theoretical platform to define and quantify spatial organization in partitions of the space that can be related to modules in a morphological analysis.

Keywords: eutactic stars; evolvability; modularity; regularity; sea urchins


Dra. Karina Alethya Acevedo Whitehouse

1.  Browning, H. M*., Acevedo-Whitehouse, K*., Gulland, F. M. D., Hall, A. J., Finlayson, J, Dagleish, M. P, Billington, K J, Colegrov,e K, Hammond, JA. (2014) Evidence for a genetic basis of urogenital cancer in the wild California sea lion. Proceedings of the Royal Society of London B. In press.

2.  Brock, P. M., Goodman ,S. J., Hall, A. J., Cruz. M., Acevedo-Whitehouse, K. (2014) Heterozygosity predicts immune variation in a wild carnivore. American Naturalist. Accepted.

3.  Martinez-Levasseur, L. M., Birch-Machin, M. A., Bowman, A., Gendron, D., Weatherhead, E., Knell, R. J., Acevedo-Whitehouse, K. (2013). Whales Use Distinct Strategies to Counteract Solar Ultraviolet Radiation. Scientific Reports 3:2386. DOI: 10.1038/srep02386

4.  Martinez-Levasseur, L. M., Gendron, D., Knell, R. J., Acevedo-Whitehouse, K. (2013) Control and target gene selection for studies on UV-induced genotoxicity in whales. BMC Research Notes 6:264 doi: 10.1186/1756-0500-6-264

5.  Brock, P. M., Hall, A. J., Goodman, S. J., Cruz, M., Acevedo-Whitehouse, K. (2013) The cost of immunity in an endangered marine mammal is modulated by anthropogenic environmental impacts. PLoS ONE 8(6). e67132. doi:10.1371/journal.pone.0067132

6.  Bowman, A., Martinez-Levasseur, L. M., Acevedo-Whitehouse, K., Gendron, D., Birch-Machin, M. A. (2013) The simultaneous detection of mitochondrial DNA damage from sun-exposed skin of three whale species and its association with UV-induced microscopic lesions and apoptosis. Mitochondrion pii: S1567-7249(13)00066-4. doi: 10.1016/j.mito.2013.04.003

7.  Jepson, P.D., Deaville, R., Acevedo-Whitehouse, K., Barnett, J., Brownlow, A., Brownell Jr, R. L., Clare, F. C., Davison, N., Law, R.J., Loveridge, J, Macgregor S.K., Morris, S., Murphy, S., Penrose, S., Perkins, M.W., Pinn, E., Seibel H., Siebert, U., Sierra E., Simpson, V., Tasker, M.L., Tregenza ,N.,  Cunningham, A.A., Fernández, A. (2013). What caused the UK’s largest common dolphin (Delphinus delphis) mass stranding event? PLoS ONE 8(4): e60953. doi:10.1371/journal.pone.0060953

8.  Pettorelli, N., Evans, D: M., Garner, T. W. J., Katzner, T., Gompper, M. E.,  Altwegg, R., Branch, T. A., Johnson, J. A.,Acevedo-Whitehouse, K., DaVolls, L.,, Rantanen, E., Gordon, I. J. (2013) Addressing gender imbalances in Animal Conservation 16: 131-133 doi:10.1111/acv.12032

9.  Brock, P., Hall, A., Goodman, S., Cruz, M., Acevedo-Whitehouse, K. (2013) Applying the tools of ecological immunology to conservation: a test case in the Galapagos sea lion. Animal Conservation 16(1): 19-31. doi:10.1111/j.1469-1795.2012.00567.x

10. Gordon, I. J., Acevedo-Whitehouse, K., Altwegg, R., Garner, T. W. J., Gompper, M. E., Katzner, T. E., Pettorelli, N., Redpath, S. (2012) What the ‘food security’ agenda means for animal conservation in terrestrial ecosystems. Animal Conservation 15(2): 115-116. doi:10.1111/j.1469-1795.2012.00541.x


 Dr. Juan Mosqueda

1.  Elba Rodríguez-Hernández, Juan Mosqueda, Ma. Elizbeth Álvarez-Sánchez, Alfonso Falcón Neri, Guillermo Mendoza-Hernández, Minerva Camacho-Nuez. The identification of a VDAC-like protein involved in the interaction of Babesia bigemina sexual stages with Rhipicephalus microplus midgut cells. Veterinary Parasitology 2012, 187(3-4) 538-541.

2.  Juan Mosqueda, Andrea Olvera, Gabriela Aguilar-Tipacamú and  G.J. Cantó. Current advances in detection and treatment of babesiosis. Current Medicinal Chemistry 2012, 19(10) 1504-1518.

3.  Mariana Dominguez, Ignacio Echaide, Susana Echaide, Silvina Wilkowsky, Osvaldo Zabal, Juan Mosqueda, Leonhard Schnittger, and Mónica Florin-Christensen. Validation and field evaluation of a competitive enzyme-linked immunosorbent assay for the diagnosis of Babesia bovis infections in Argentina. Clinical and Vaccine Immunology, 2012, 19(6) 924-928.

4.  Massaro W. Ueti, Yunbing Tan, Shira Broschat, Elizabeth J. Castañeda Ortiz, Minerva Camacho-Nuez, Juan J. Mosqueda, Glen A. Scoles, Matthew Grimes, Kelly A. Brayton and Guy H. Palmer. Expansion of variant diversity associated with a high prevalence of pathogen strain superinfection under conditions of natural transmission. Infection and Immunity, 2012, 80(7), 2354-2360.

5.  Juan Joel Mosqueda Gualito, Alfonso Falcón Neri, Juan Alberto Ramos Aragón, Germinal Jorge Canto Alarcón, Minerva Camacho-Nuez. Genome and molecular strategies for bovine babesiosis control. Revista Mexicana de Ciencias Pecuarias 2012; 3(Supl 1):51-59.

6.  Germinal J. Canto, Roberto I. Guerrero, Andrea M. Olvera-Ramírez, Feliciano Milián, Juan Mosqueda, Gabriela Aguilar-Tipacamú. Prevalence of Fleas and Gastrointestinal Parasites in Free-Roaming Cats in Central Mexico. PLoS ONE 2013; 8(4):1-6.

7.  D.Flores, Y. Minichiello, F.R. Araujo, V. Shkap, D. Benítez, I. Echaide, P. Rolls, J. Mosqueda, G.M. Pacheco, M. Petterson, M. Florin-Christensen, L. Schnittger. Evidence for Extensive Genetic Diversity and Substructuring of the Babesia bovis Metapopulation. Transboundary and Emerging Diseases 2013. 60 (Suppl. 2) 131-136.

8.  Octavio Merino, Sandra Antunes, Juan Mosqueda, Juan A. Moreno-Cid, José M. Pérez de la Lastra, Rodrigo Rosario-Cruz, Sergio Rodríguez, Ana Domingos, José de la Fuente. Vaccination with proteins involved in tick-pathogen interactions reduces vector infestations and pathogen infection. Vaccine 2013, 31; 5889-5896.

9.  Sandra Antunes, Octavio Merino, Juan Mosqueda, Juan A Moreno-Cid, Lesley Bell-Sakyi, Rennos Fragkoudis, Sabine Weisheit, José M Pérez de la Lastra, Pilar Alberdi, Ana Domingos and José de la Fuente. Tick capillary feeding for the study of proteins involved in tick-pathogen intercations as potential antigens for the control of tick infestation and pathogen infection. Parasites & Vectors. 2014, 7:42. 1-12.

10. Nathan E Stone, Pia Olafson, Ronald B Davey, Greta Buckmeier, Deanna Bodine, Lindsay C Sidak-Loftis, Roberta A Duhaime, Robert J Miller, Juan Mosqueda, Glen A Scoles, David M Wagner and Joseph D Busch. Multiple mutations in the para-sodium channel gene are associated with pyrethroid resistance in Rhipicephalus microplus from the United States and Mexico. Parasites & Vectors. Aceptado.

11. Eduardo Vallejo Esquerra, David R. Herndon, Francisco Alpirez Mendoza, Juan Mosqueda, and Guy H. Palmer. Anaplasma marginale superinfection attributable to pathogen strains with distinct genomic backgrounds. Infection and Immunity. Aceptado.

12. Sandra Antunes, Octavio Merino, Joana Lerias, Juan Mosqueda, José de la Fuente, Ana Domingos. Artificial feeding of Rhipicephalus microplus female ticks with anti calreticulin serum do not influence tick and Babesia bigemina acquisition. Ticks and Tick-Borne Diseases. Aceptado.


 Dr. Rubén Pineda López


1. Pineda-López R. 2011. Aves acuáticas de la zona semiárida de Querétaro. Universidad Autónoma de Querétaro. ISBN: 978-607-7740-75-9. México. 130 p.

2. Maruri A. B., A. I. García-Valdés, R. Pineda-López y J. B. Hernández-Díaz. 2013. Las Aves del Jardín Botánico Regional de Cadereyta: Una presencia interpretada. Consejo de Ciencia y Tecnología del Estado de Querétaro. Querétaro. ISBN: 978-607-7710-33-2. México. 97 p.

3. Pineda-López R. y J. R. Verdú-Faraco. 2013. Cuaderno de Prácticas: Medición de la biodiversidad: diversidades alfa, beta y gamma. Universidad Autónoma de Querétaro. Querétaro. ISBN: 978-607-513-057-6. México. 120 p.

Capítulos de Libro

1.Ortega-Álvarez R, I. MacGregor-Fors, R. F. Pineda-López, R. Pineda-López, P. Ramírez-Bastida e I. Zuria. 2013. México. En: MacGregor-Fors y R. Ortega-Álvarez Eds. Ecología Urbana: Experiencias en América Latina. México:82-99. ISBN: 978-607-00-6869-0.

Artículos Arbitrados

1.Pineda-López R., A. Arellano-Sanaphre y C. De la Vega Aguirre. 2013. Registros nuevos y notables de aves acuáticas en Querétaro y estados adyacentes. Huitzil 14:1-6.

2.Pineda-López R., A. Malagamba, I. Arce-Acosta y J. A. Ojeda-Orranti. 2013. Detección de aves exóticas en parques urbanos del centro de México. Huitzil 14:56-67.

3.Calderón-Patrón J. M., C. E. Moreno, R. Pineda-López, G. Sánchez-Rojas e I. Zuria. 2013. Vertebrate dissimilarity due to turnover and richness differences in a highly beta-diverse region: the role of spatial grain size, dispersal ability and distance. PLOS ONE 8(12):e82905.

4.Pérez-Crespo M. J., J. Fonseca, R. Pineda-López, E. Palacios y C. Lara. 2013. Foraging guild structure and niche characteristics of waterbirds in an epicontinental lake in Mexico. Zoological Studies 52: 54.

5.Malagamba-Rubio A., I. MacGregor-Fors y R. Pineda-López. 2013. Comunidades de aves en áreas verdes de la ciudad de Santiago de Querétaro, México. Ornitología Neotropical 24:371-386.

6. Granja-Fernández R., D. Herrero-Pérezrul, R. A. López-Pérez, L. G. Hernández-Moreno, F. A. Rodríguez-Zaragoza, R. Jones y R. Pineda-López. 2014. Ophiuroidea (Echinodermata) from coral reefs in the Mexican Pacific. ZooKeys 406:101-145.

7.Hernández-Díaz J. B., A. Acosta-Ramírez, M. Tepos-Ramírez y R. Pineda-López. 2014. Adiciones al inventario avifaunístico del estado de Querétaro. Aceptado.


 M.V.Z. Marco A. Asprón Pelayo

E. P. López-DamiánA, T. FiordelisioA, M. A. LammogliaB, M. AlarcónB, M. AsprónC  and C. S. GalinaA

A Universidad Nacional Autónoma de México, Mexico City, Mexico; B Universidad Veracruzana, Tuxpan, México;

C Universidad Autónoma de Querétaro, Querétaro, México

Reproduction, Fertility and Development 25(1) 226-226

Published: 4 December 2012


Accurate evaluation of bovine embryos for assessing developmental stage and quality is critical to the success of any embryo transfer program. However, this evaluation process has been reported to be highly subjective in Bos indicus (BI) and can vary as much as 23% compared with that of Bos taurus (BT). These differences in assessment may be related to the quantity of lipid droplets (LD) within the embryo, which has been shown to have a negative effect in cryopreserving embryos. The aim of the present study was to characterize the number and size of LD in differentdevelopmental stages of fresh embryos from BI and BT and to compare LD across the three different embryo qualitygrades (1 = excellent or good, 2 = fair, and 3 = poor). Nonsurgical embryo collection was performed 7 days postinsemination in 10 BI and 10 BT females. Forty-eight embryos were evaluated for stage and grade using stereoscopicmicroscopy, processed for transmission electron microscopy, and stained with Nile red. Digitalized images were analyzed with ImageJ (National Institutes of Health, Bethesda, MD, USA), contour of lipid droplets were designed, and values of perimeter, area, and fluorescence intensity were assessed. Nonparametric statistical analysis (Mann–Whitney) was utilized. There was no difference in LD number for BT or BI for morulae and blastocyst; however, BI morulae presented larger LD compared with blastocyst stage embryos (286 μm v. 223 μm; P < 0.05). Likewise, BITF cells had more LD compared with inner cell mass (ICM) cells (48 v. 36; P < 0.05). BT TF cells exhibited larger LDcompared with ICM cells (149 μm v. 128 μm; P < 0.05), while BI embryos exhibited a larger area of LD in the ICMcompared with the TF (591 μm v. 472 μm; P < 0.05). In all embryos, BI contained more lipid droplets than BT (78 v.49; P < 0.05). Across all quality grades (good, fair, and poor) there was no difference in the number of LD in BTembryos; however, BI grade-3 embryos presented more LD than grade-1 (36 v. 25). BT embryos LD were larger than BI LD (907 μm v. 625 μm; P < 0.05). Fluorescence images showed higher arbitrary units of fluorescence (auf) for LD in BI compared with BT embryos (386 auf v. 280 auf; P < 0.05). These results suggest that BI embryos contain moreand smaller LD than BT embryos and the LD described for BI embryo quality grade 1 are larger than those of qualitygrades 2 and 3, and even though the number of LD in morulae and blastocyst stage embryos are not different LD sizeis reduced as development occurs.

Research funding provided by UNAM-DGAPA-PAPIIT IN200810.

Dr. Milian Suazo F., Canto Alarcon G

Publicaciones en revistas indizadas